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1 Self-care advice from NICE details: 8 Explain that symptom relief and rest are the most appropriate management Advise that antibiotics and antihistamines are ineffective and may cause adverse effects Adequate fluid should be taken during the course of the illness Healthy food is recommended although no specific diet or mineral or vitamin supplementation is necessary Adequate rest is advised however it is not necessary to stay off work or school and normal activity will not prolong the illness Transmission cannot be completely prevented but basic good hygiene can help prevent the spread: wash hands frequently with soap and hot water Treatment Product information Otrivine Extra Dual Relief Nasal Spray Product Information Full information can be found in the Summary of Product Characteristics Otrivine Extra Dual Relief 0.5 mg/ml + 0.6 mg/ml nasal spray, solution (xylometazoline hydrochloride, ipratropium bromide)

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Network analysis of the metabolome and transcriptome reveals novel regulation of potato pigmentation